Claudia Köhler's Lab

Research

Mechanisms of Seed Development and Plant Speciation

Our lab has a general interest in genetic and epigenetic mechanisms governing seed development and plant speciation. We are strongly interested in understanding the role of the endosperm in establishing postzygotic hybridization barriers between plants of different ploidy as well as between related plant species. We currently have five major lines of research in the lab:

- Non-cell autonomous signaling mechanisms regulating seed coat growth
- Epigenetic mechanisms determining irreversible cell fate decisions
- Regulation and function of imprinted genes
- Underlying basis of postzygotic interploidy hybridization barriers (triploid block)
- Mechanisms of unreduced gamete formation in plants

We apply forward genetic screens, reverse genetic approaches, as well as transcriptional and epigenome profiling using the model organisms Arabidopsis thaliana, Arabidopsis lyrata, Capsella and Primula to identify the underlying mechanisms of seed development and plant speciation.